Dietary and nutritional measures are the initial strategy for gastroparesis. When they fail to reach their intended goals, a defined next step in management is indicated.
The prior step was dietary and nutritional management: a small particle, low-fat diet, with enteral nutrition via jejunostomy tube or parenteral nutrition where oral intake was insufficient. The targets were symptom relief and enhanced gastric emptying. Non-achievement of those targets triggers escalation to this protocol.
Pharmacologic treatment targeting gastric motility — drawing on several recognised drug classes — is recommended to improve gastric emptying and reduce gastroparesis symptoms. The complete agent selection, sequencing, and clinical considerations are available in the full protocol.
Improved gastric emptying and reduced gastroparesis symptoms.
DOI: 10.14309/ajg.0000000000001874
In patients with idiopathic and DG, pharmacologic treatment should be considered to improve GE and GP symptoms, considering benefits and risks of treatment (conditional recommendation, low quality of evidence).
In patients with GP, use of antiemetic agents is suggested for improved symptom control; however, these medications do not improve GE (conditional recommendation, low quality of evidence).
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