Gastrointestinal luminal tuberculosis does not always present as a straightforward first episode. When the disease has recurred, when drug resistance is suspected or confirmed, or when the patient's clinical condition is serious, the treatment approach differs from that used in uncomplicated intestinal tuberculosis and requires a more carefully structured regimen.
This protocol addresses patients with gastrointestinal luminal tuberculosis presenting in any of the following contexts:
Management involves a structured, multi-drug anti-tuberculosis regimen delivered in sequential phases — the precise drug selection, phasing, and continuation strategy are defined in the full protocol below.