Treating Functional Dyspepsia in Helicobacter pylori Infection
Clinical scenario
This protocol addresses patients with functional dyspepsia (FD) who have confirmed Helicobacter pylori infection. The presence of H. pylori is an important clinical finding in this context, as eradication therapy is an efficacious treatment for H. pylori-positive patients with FD.
Treatment approach — partial overview
Following appropriate management of the H. pylori infection, the structured protocol for this scenario includes referral for gut-brain behavioural therapy — a class of psychological intervention targeting symptom burden. The complete regimen, including which specific modalities apply and the sequencing, is available in the full protocol.
References
DOI: 10.1136/gutjnl-2022-327737
- Eradication therapy is an efficacious treatment for H. pylori-positive patients with FD.
- CBT and metacognitive therapy may be an efficacious treatment for global symptoms in FD (recommendation: weak, quality of evidence: very low).
- Hypnotherapy may be an efficacious treatment for global symptoms in FD (recommendation: weak, quality of evidence: very low).
- Stress management approaches may be an efficacious treatment for global symptoms in FD (recommendation: weak, quality of evidence: very low).
- Interpersonal psychodynamic informed psychotherapy may be an efficacious treatment for global symptoms in FD (recommendation: weak, quality of evidence: very low).
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