Treatment of Fuchs' Endothelial Corneal Dystrophy in Patients Under 50

Clinical Scenario

This protocol addresses patients under 50 years of age with visually significant Fuchs' endothelial corneal dystrophy (FECD) who present with a clear, prepresbyopic crystalline lens and a deep anterior chamber — a clinically distinct presentation that calls for carefully staged surgical planning.

Treatment Approach

In this scenario, management involves a staged endothelial keratoplasty approach undertaken in a specific sequence relative to lens status. The full surgical protocol — including timing, sequencing, and decision criteria — is detailed in the structured regimen. Access the complete protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1146/annurev-vision-091718-014852

Staged EK prior to cataract surgery may be applied in patients under 50 years of age with visually significant FECD and a clear, prepresbyopic lens and deep anterior chamber.

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