This protocol covers superficial frostbite of the extremities at grades 1 and 2 — a range that includes presentations without cyanosis and those with cyanosis limited to the distal phalanx.
Superficial extremity frostbite, grades 1 and 2, encompasses injuries at the superficial tissue level. Presentations range from superficial grade 1 injury without cyanosis to superficial grade 2 with cyanosis of the distal phalanx.
For adult patients with an expected inpatient stay exceeding 48 hours, intravenous iloprost infusion may be considered as part of the management approach. Admission to monitored care with continuous telemetry is required for the duration of infusion therapy. The complete protocol — including dosing approach, titration schedule, and duration — is available in the full regimen below.