Sleep-Disordered Breathing and Nocturnal Hypoventilation in Friedreich Ataxia
This protocol addresses the management of Friedreich ataxia in individuals who also present with sleep-disordered breathing, sleep apnea, and/or nocturnal hypoventilation — a clinical picture with implications for fatigue, daytime sleepiness, overnight sleep quality, gas exchange, and cardiac function.
Specific clinical scenario: Friedreich ataxia with co-occurring sleep-disordered breathing, sleep apnea, and/or evidence of nocturnal hypoventilation, where these factors affect fatigue, sleepiness, sleep quality, blood gas parameters, and cardiac function.
In this setting, a form of non-invasive ventilatory support is suggested as the intervention of choice. The structured protocol specifies the approach in detail — including patient selection, implementation considerations, and the clinical targets it addresses — none of which are reproduced here in full.
References
In individuals with Friedreich ataxia and sleep disordered breathing/sleep apnea and/or evidence of nocturnal hypoventilation, we suggest non-invasive ventilation be implemented to assist in fatigue; sleepiness; quality of night time sleep; blood gas parameters; and cardiac function
DOI: 10.1186/s13023-022-02568-3
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