Painful neuropathy is a recognised complication of Friedreich ataxia that requires targeted clinical management. Active treatment is preferred over no treatment in individuals with this presentation.
This protocol applies to patients with Friedreich ataxia who have painful neuropathy (neuropathic pain). Evidence-based guidance supports the use of specific pharmacological interventions in this population rather than watchful waiting alone.
Management centres on oral medications — with agents such as gabapentin among those considered — as the primary approach. Topical agents are available as an alternative option. The full protocol specifies which agents apply and under what clinical conditions.
DOI: 10.1186/s13023-022-02568-3
We suggest the use of oral medication over no medication in individuals with Friedreich ataxia who have painful neuropathy
Neuropathic pain may be treated with gabapentin, pregabalin, lamotrigine, amitriptyline or duloxetine
We suggest the use of topical agents over no treatment in the management of neuropathic pain in Friedreich ataxia
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