When Friedreich ataxia and diabetic ketoacidosis occur together, the management of the acute metabolic crisis requires specific consideration of how Friedreich ataxia affects the treatment response.
Patients with Friedreich ataxia who present with diabetic ketoacidosis represent a distinct clinical scenario. The characteristics of Friedreich ataxia influence glucose metabolism in ways that affect how this comorbidity is managed.
Insulin therapy is the cornerstone of treatment in this setting. The protocol addresses specific dose considerations arising from the interaction between Friedreich ataxia and insulin handling — the complete structured regimen is available via the link below.
DOI: 10.1186/s13023-022-02568-3
Individuals with Friedreich ataxia and diabetic ketoacidosis may need a higher dose of insulin therapy as a result of insulin deficiency and insulin resistance in Friedreich ataxia.
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