La thrombose de la veine rénale survenant conjointement à une thrombose veineuse profonde proximale — thrombus impliquant les veines poplitée, fémorale ou iliaque — représente une situation thromboembolique veineuse cliniquement significative qui nécessite une prise en charge rapide et structurée.
DOI: 10.3949/ccjm.91a.22090
Proximal DVT is defined as thrombus in the popliteal, femoral, or iliac veins.
The 2021 CHEST guidelines recommend treating proximal DVT with anticoagulation for at least 3 months.
Proximal DVT confers up to a 50% risk of pulmonary embolism if left untreated, so treatment with anticoagulation is recommended even in the absence of symptoms ("incidental DVT").
The 2021 CHEST guidelines recommend the use of DOACs over warfarin whenever possible, based on data showing a lower risk of major bleeding (especially intracranial hemorrhage) with DOACs vs warfarin (strong recommendation with moderate-certainty evidence).
Use of an inferior vena cava filter should be considered only in patients deemed to have an unacceptably high bleeding risk.
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