L'uvéite antérieure est une manifestation oculaire reconnue de la sarcoïdose nécessitant une prise en charge rapide et ciblée afin de supprimer l'inflammation intraoculaire et de prévenir les complications menaçant la vision.
Anterior uveitis usually can be managed with local therapy using corticosteroid eye drops to suppress inflammation and cycloplegic eye drops to suppress pain and avoid intraocular scarring.
If greater than 10 mg prednisone is needed to control the disease, then corticosteroid-sparing drugs should be used.
Cytotoxic drugs such as methotrexate, azathioprine, and mycophenolate mofetil have been used with success.
Due to its flexibility, effectiveness and the ability to provide ongoing therapy and treat extraocular aspects of sarcoidosis simultaneously, cytotoxic therapy, usually cytotoxic agents, has been the mainstay of therapy.
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