La gonarthrose est une affection articulaire fréquente pour laquelle les recommandations cliniques soutiennent de manière constante le traitement topique appliqué directement sur le genou atteint dans le cadre de la prise en charge de première ligne. Plusieurs organismes majeurs de recommandations ont évalué et émis des recommandations en faveur de cette approche.
Topical NSAIDs were uniformly strongly recommended for knee OA by all guidelines and were strongly and conditionally recommended for hand OA by EULAR and ACR/AF, respectively, with the strength of recommendation influenced by practicality of using topical agents on finger joints.
In contrast, topical capsaicin was conditionally or weakly recommended for knee OA by ACR/AF and VA/DOD, but conditionally recommended against by OARSI.
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