Treatment of Mild Acute Food Protein-Induced Enterocolitis Syndrome with 1–2 Episodes of Vomiting
Mild acute FPIES presenting with limited vomiting and no lethargy represents a specific, well-defined scenario with a distinct management approach — different from more severe or atypical presentations.
Clinical scenario
- Acute food protein-induced enterocolitis syndrome (FPIES), mild severity
- 1–2 episodes of vomiting (emesis)
- No lethargy
Mild-to-moderate acute FPIES can resolve with oral rehydration, including breast-feeding, at home.
Treatment approach
In this mild presentation, the foundational step is oral rehydration support — using breast-feeding or appropriate clear fluids. Depending on the child's age, a further measure to manage vomiting may be considered alongside this.
The complete step-by-step regimen — including eligibility, specific agents, and sequencing — is in the full protocol below.
Treatment goal
Resolution of the acute reaction approximately 4–6 hours from onset
References
DOI: 10.1016/j.jaci.2016.12.966
- 1–2 Episodes of emesis
- No lethargy
- Mild-to-moderate acute FPIES can resolve with oral rehydration, including breast-feeding, at home
- Attempt oral rehydration (eg, breast-feeding or clear fluids)
- Monitor for resolution about 4–6 h from the onset of a reaction
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