Fibrous dysplasia of bone
ICD-10 M85.0 · ICD-11 FB80.0.1

Treatment of Fibrous Dysplasia of Bone with Neuropathic Bone Pain (Burning or Stabbing)

When bone pain in fibrous dysplasia presents with neuropathic features — specifically burning or stabbing pain — the clinical picture calls for a targeted approach that goes beyond standard analgesia.

Clinical Scenario

Bone pain in fibrous dysplasia accompanied by neuropathic pain features such as burning or stabbing pain. The treatment goal in this scenario is neuropathic bone pain relief.

Approach (partial)

Management follows an atypical analgesic pathway using neuropathic-targeting agents — a distinct strategy from conventional pain ladders.

The complete regimen, agent selection criteria, and sequencing are available in the full structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

If neuropathic features such as burning or stabbing pain are present, consider an atypical analgesic ladder, e.g. amitriptyline, gabapentin, pregabalin and duloxetine.

The strategy is to induce symptom remission.

DOI: 10.1186/s13023-019-1102-9

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