Essential Tremor: What to Do When a Single Agent Does Not Adequately Control Limb Tremor
Essential tremor is a common movement disorder characterised by persistent action tremor, most notably affecting the limbs. In some patients, treatment with a single agent does not achieve adequate tremor control, and a structured next step is required.
This protocol applies when monotherapy with propranolol or primidone has not adequately controlled limb tremor and a combination approach is being evaluated.
Treatment approach (partial)
The protocol involves a specific combination of two established agents used together — evidence indicates this may provide additional benefit without a proportional increase in side effects.
The complete regimen, sequencing, and clinical considerations are detailed in the full protocol.
References
DOI: 10.4103/0972-2327.83097
- When monotherapy with propranolol or primidone does not adequately control limb tremor, these 2 drugs can be used in combination.
- It has been shown that there may be an added beneficial effect without an increase in side effects.
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