Adults with Type 2 diabetes and hypertension have specific blood pressure targets and a defined escalation path when initial treatment falls short. This protocol addresses the next step after a first-line agent fails to achieve control.
Patient has concurrent Type 2 diabetes and hypertension. The treatment goal is SBP <130 mm Hg and DBP <80 mm Hg.
A first-line antihypertensive agent (thiazide-type diuretic, long-acting calcium channel blocker, ACE inhibitor, or ARB) was initiated but did not achieve the goals of SBP <130 mm Hg and DBP <80 mm Hg. This protocol defines what comes next.
The approach involves sequentially adding and titrating agents from complementary first-line antihypertensive classes. The full selection logic, combination strategy, and sequencing are in the complete protocol.
SBP <130 mm Hg and DBP <80 mm Hg.
DOI: 10.1161/CIR.0000000000001356
In adults with T2D and hypertension, antihypertensive drug treatment should be initiated at an SBP of ≥130 mm Hg with a treatment goal of <130 mm Hg, with encouragement to achieve an SBP <120 mm Hg to reduce CVD morbidity and mortality.
In adults with T2D and hypertension, all first-line classes of antihypertensive agents (ie, thiazide-type diuretics, long-acting CCB, ACEi, and ARB) are useful and effective for BP lowering.
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