Tratamiento de la Pancreatitis Aguda en Necrosis Pancreática Infectada
La necrosis pancreática infectada es una complicación grave de la pancreatitis aguda que modifica significativamente el manejo respecto al enfoque utilizado en la enfermedad estéril. Identificar correctamente a esta subpoblación es esencial: la estrategia terapéutica es distinta y más específica.
References
DOI: 10.14309/ajg.0000000000002645
While antibiotics should not be used in patients with sterile necrosis, antibiotics are an important part of treatment in infected necrosis along with debridement/necrosectomy.
Because the infection will likely seed the necrosis, and the necrosis will be difficult to penetrate, antibiotics chosen should be known to penetrate the necrosis, such as carbapenems, quinolones, cephalosporins, and metronidazole.
However, in most patients, those clinically stable, the initial management of infected necrosis should be a 30-day course of antibiotics before surgery to allow the inflammatory reaction to become better organized.
Some patients may avoid drainage altogether because the infection may completely resolve with antibiotics.
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