Treatment of Erythema Multiforme with Mild or Moderate Mucosal Involvement

Erythema multiforme can affect mucosal surfaces across a spectrum of severity. When involvement is mild or moderate, management focuses on the mucosal lesions directly, with a targeted localised approach rather than systemic escalation.

This protocol applies to patients presenting with erythema multiforme in whom mucosal involvement is confirmed but classified as mild or moderate — a sub-population that warrants its own distinct management pathway.

Care in this setting centres on a high-potency topical anti-inflammatory agent directed at the mucosal lesions, combined with supportive oral hygiene measures. The specific agents, their formulations, and the full clinical decision pathway are detailed in the complete protocol.

Agent selection, application details, and adjunct measures are available in full via the link below.