Treatment of Epilepsy with Myoclonic-Atonic Seizures in Adults 16 Years and Older
Clinical Scenario
This protocol applies to adults aged 16 years and older with epilepsy with myoclonic-atonic seizures — a seizure type in which a myoclonic seizure occurs and is immediately followed by an atonic seizure.
Treatment Approach
In adults whose seizures have not been adequately controlled, nonpharmacologic interventions represent a key category of management options. The complete protocol details specific approaches, selection criteria, and the full sequencing — access it below.
Treatment Goals
The primary objective is decreased frequency or elimination of seizures, with improvement in quality of life in appropriately selected patients.
References
- Myoclonic seizure occurs, followed by an atonic seizure.
- Up to 30% of patients with epilepsy can have medically refractory epilepsy.
- These patients have continued seizures despite appropriate AED therapy.
- For patients with seizures that are not controlled with these agents, alternative treatments include surgical resection of the seizure focus, ketogenic diets, vagus nerve stimulators, and implantable brain neurostimulators.
- Surgical resection of the seizure focus in appropriately selected patients often results in decreased frequency or elimination of seizures with improvement in quality of life.
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