This protocol applies to children under the age of 16 years presenting with epilepsy characterised by myoclonic seizures. The typical presentation involves rhythmic myoclonic jerks of the shoulders and arms with tonic abduction that results in progressive lifting of the arms during the seizure.
Management begins with monotherapy — the selection of a single indicated oral agent — rather than combination therapy from the outset. The full structured regimen, including the specific agents, dosing framework, and escalation criteria, is available via the protocol below.