This protocol applies to adults aged 16 years and older presenting with generalized seizures. Onset is typically bilateral and symmetric, although variants with asymmetry — including head and eye deviation — are possible.
When first-line monotherapy does not achieve adequate control, management may escalate to combination therapy with two or more antiepileptic drugs — though the specific agents, sequencing, and decision criteria vary by seizure type and patient factors.
Typically bilateral and symmetric, although variants with asymmetry, including head and eye deviation, are possible.
Younger adults (16 to 59 years of age).
Monotherapy with all indicated AEDs should be attempted before initiating combination therapy.
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