First-Line Treatment of Epilepsy: Focal (Partial) Seizures in Adults Ages 16–59
Clinical Scenario
This protocol addresses adults between 16 and 59 years of age who present with focal (partial) seizures — seizures originating within networks limited to one hemisphere. These may manifest as subjective (aura), motor, autonomic, or dyscognitive features.
Treatment Approach
The recommended first step is initiating monotherapy with a single antiseizure agent selected from a group of agents with Level A evidence for focal (partial) seizures in this age group.
References
- Seizure originating within networks limited to one hemisphere characterized by subjective (aura), motor, autonomic, and dyscognitive features
- Younger adults (16 to 59 years of age)
- Treatment should begin with monotherapy.