What Is the First-Line Treatment for Ebola Virus Disease?
Ebola virus disease is managed from the outset with structured symptomatic care. The first-line protocol addresses the principal symptoms — fever, mild pain, and nausea or vomiting — with specific interventions for both adult and paediatric patients.
Treatment Approach
The first-line approach is symptomatic. An analgesic-antipyretic agent is used for fever and mild pain, and antiemetic therapy is selected to control nausea and vomiting — with dosing structured separately for adults and children. The full regimen, including agent selection and structured dosing, is available via the link below.
References
Adults: 1 g paracetamol PO/IV every 6–8 hours. Maximum dose 4 g every 24 hours or (2 g if history of chronic liver disease).
All other children: 10–15 mg/kg 6 hourly, maximum dose 60 mg/kg/day.
Adults: 8 mg PO every 12 hours or 4 mg IV every 8 hours as needed.
Only for adults: use 12.5–25 mg PO every 4–6 hours as needed (can provide QT interval).
View source ↗