Ebola virus disease (EVD) is a severe, acute viral illness requiring prompt structured management. The first-line protocol focuses on controlling the symptoms that drive early deterioration — fever, pain, and gastrointestinal distress.
This protocol applies to first-line management of Ebola virus disease. Key symptomatic targets include fever, mild pain, and nausea with vomiting — addressed through a sequenced, weight- and age-adjusted approach with specific considerations for patients with relevant comorbidities.
Management is symptomatic. An antipyretic/analgesic agent is used for fever and mild pain, and antiemetic agents are used for nausea and vomiting. The full protocol specifies which agents to use, in what order, by which route, and at what doses for adults versus children — including adjustments for specific underlying conditions. These details are in the complete regimen.