Treatment of Eales Disease in Active Retinal Perivasculitis (Inflammatory Stage)
When Eales disease presents in its active perivasculitis stage, controlling retinal inflammation promptly is the priority. The clinical scenario below defines when this management approach applies.
Clinical scenario
Active retinal perivasculitis (inflammatory stage) of Eales disease, without a positive Mantoux test.
Corticosteroid therapy is the established mainstay in this inflammatory stage. The specific route and strategy depend on the extent of retinal involvement and whether associated macular changes are present.
The complete structured regimen — dosing approach, route selection by extent of involvement, and adjustments for macular involvement — is available in the full protocol.
References
DOI: 10.1016/s0039-6257(02)00288-6
Corticosteroids remain the mainstay of therapy in the active perivasculitis stage of Eales disease.
Systemic corticosteroids have been found to be beneficial in the active perivasculitis stage.
In case of associated macular edema, one may add periocular depot steroid injection.
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