Treatment of DRESS Syndrome in Children Under 18 Years
DRESS syndrome presenting in patients under 18 years of age requires a tailored clinical approach. The pediatric population occupies a distinct therapeutic context, and guidance in this age group draws heavily on adult data given the limited dedicated evidence base.
Clinical Scenario
This protocol applies to children under 18 years of age diagnosed with DRESS syndrome. The treatment framework in this population broadly parallels that used in adults, though the evidence supporting specific interventions in pediatric patients remains limited.
Treatment Approach
Systemic immunomodulatory therapy is among the approaches that have been considered in pediatric DRESS — the full protocol details the specific options evaluated for this age group and the clinical context guiding their use.
References
- The treatment of pediatric DRESS is similar to that for adults.
- In some cases, corticosteroid pulses, antivirals, IVIg or cyclosporine have been proposed, but no robust studies have established the role of these therapies in the treatment of DRESS in children.
DOI: 10.1016/j.annder.2025.103381
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