A subset of patients with diabetic neuropathy develops gustatory sweating — a rare form of sudomotor dysfunction in which food consumption (or in some cases the smell of food alone) triggers excessive sweating confined exclusively to the head and neck region.
The evidence-based approach involves a topical antimuscarinic agent applied to the affected area on a regular daily basis. The complete regimen, including the specific agent, application instructions, and clinical follow-up guidance, is detailed in the structured protocol below.
The primary objective is attenuation (reduction) of gustatory sweating.
DOI: 10.2337/dc16-2042
A rare form of sudomotor dysfunction is gustatory sweating that comprises excessive sweating limited exclusively to the head and neck region triggered by food consumption or, in some cases, the smell of food.
The efficacy of the topical antimuscarinic agent glycopyrrolate in the treatment of gustatory sweating was confirmed in a randomized controlled trial, and daily application attenuates this complication in most patients for at least 24 h.
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