Treatment of Diabetic Neuropathy in Diabetic Gastroparesis with Early Satiety and GI Symptoms
Clinical Scenario
This protocol applies to patients with diabetic neuropathy presenting in the context of diabetic gastroparesis — a complication characterised by delayed gastric emptying. Providers are encouraged to document the presence of characteristic gastroparesis symptoms when taking the patient's history.
- Early satiety
- Fullness
- Bloating
- Nausea
- Vomiting
- Dyspepsia
- Abdominal pain
Treatment Approach (Partial)
For severe cases of diabetic gastroparesis that have not responded to other therapies, a short-term course of a prokinetic agent may be considered — used only briefly and under specific conditions.
Full regimen details, criteria, and sequencing are available in the complete protocol.
References
DOI: 10.2337/dc16-2042
- As part of a medical history, providers are encouraged to document symptoms of gastroparesis, such as early satiety, fullness, bloating, nausea, vomiting, dyspepsia, and abdominal pain.
- Consider short-term metoclopramide in the treatment of diabetic gastroparesis.
- Only metoclopramide, a prokinetic agent, is approved by the FDA for the treatment of gastroparesis.
- It should be reserved for severe cases that are unresponsive to other therapies.
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