Treatment of Cytomegalovirus Gastroenteritis and Hepatitis in Mild CMV Colitis or Mild CMV Esophagitis
Clinical Scenario
This protocol applies to patients with Cytomegalovirus (CMV) gastrointestinal disease presenting as
mild CMV colitis or mild CMV esophagitis.
Mild severity of disease is central to both patient selection and the choice of treatment strategy.
Treatment Approach
For patients with mild CMV colitis or mild CMV esophagitis, oral antiviral therapy is the recommended approach.
The full regimen — specific agent, dosing, frequency, treatment duration, and monitoring — is available in the complete protocol.
Treatment Goal
Resolution of gastrointestinal signs and symptoms of CMV disease; therapy is continued until clinical resolution is achieved.
References
- Valganciclovir 900 mg PO every 12 hours can be used in patients with mild disease (AIII).
- Oral valganciclovir can be used in patients with mild disease (AIII).
- 21–42 days or until signs and symptoms have resolved (AIII).
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