Treatment of Specific Granulomatous Cutaneous Sarcoidosis with Cosmetically Important or Generalized Lesions
When cutaneous sarcoidosis manifests as specific (granulomatous) lesions that are cosmetically significant or involve several to generalized areas of skin, local approaches are typically insufficient. This presentation calls for a structured pharmacotherapy regimen.
Clinical Scenario
Specific (granulomatous) cutaneous sarcoidosis lesions that are cosmetically important, or that are multiple and generalized — a pattern where local therapy alone is unlikely to achieve adequate disease control and systemic pharmacotherapy is required.
Treatment Approach
For very severe or extensive cases of this type, anti-TNF therapy is among the recognized options. The full structured regimen — including agent selection and sequencing — is detailed in the protocol.
References
- If lesions do not respond to local therapy or if skin disease is more generalized, some type of pharmacotherapy is required.
- For very severe cases, anti-TNF therapy, such as infliximab may have a role.
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