Treatment of Cutaneous Leishmaniasis Caused by Leishmania tropica, L. infantum/donovani, or L. aethiopica

Clinical Scenario

Confirmed or suspected cutaneous leishmaniasis in which the causative organism is L. tropica, L. infantum/donovani, or L. aethiopica. Species identification and clinical presentation both inform management.

First-Line Approach

For a specific subset of eligible patients, a conservative local management strategy represents one accepted first-line option — full eligibility criteria, the complete decision algorithm, and all additional therapeutic options are available only in the full protocol.

Regimen details, dosing, sequencing, and eligibility thresholds are not shown here.

Treatment Goal

Complete reepithelialization (healing) of the cutaneous lesion.