Cutaneous Leishmaniasis Caused by Leishmania naiffi with Only a Few Non-Cosmetically Disfiguring Lesions

This protocol applies to patients with cutaneous leishmaniasis in whom the causative species is Leishmania naiffi and whose skin involvement is limited to only a few lesions that are not cosmetically disfiguring.

When L. naiffi infection presents with only a small number of non-cosmetically disfiguring cutaneous lesions, the clinical picture differs meaningfully from more extensive or disfiguring disease — and the evidence-based management approach differs accordingly.

In this specific presentation, a watchful, expectant strategy is considered appropriate. The clinical goal is complete reepithelialization — full healing — of the cutaneous lesion. The full protocol details the evidence-based steps and decision criteria for this scenario.