Cutaneous leishmaniasis caused by Leishmania mexicana: when wound care alone has not achieved healing
Clinical scenario
This protocol covers cutaneous leishmaniasis caused by Leishmania mexicana in patients who did not achieve complete healing of their lesion(s) through an initial period of watchful waiting with simple wound care.
Previous line — reason for escalation
The prior approach — simple wound care without antileishmanial medication, used when lesions were limited, not cosmetically disfiguring, and expected to be self-limiting — did not lead to complete reepithelialization of the cutaneous lesion. That failure of healing is the indication for moving to the next structured regimen.
Treatment approach (partial overview)
When wound care has not achieved healing and multiple lesions are present, local treatment options become the focus — the full protocol specifies the modalities and the criteria that determine which is most appropriate. The treatment goal is complete reepithelialization of the cutaneous lesion.
Goal: complete reepithelialization
References
DOI: 10.1111/jtm.12089
- Treatment of L. mexicana
- More than three lesions with diameter <30 mm — local treatment:
- Cryotherapy/local infiltration with antimonials
- 15% Paromomycin/12% methylbenzethonium chloride ointment
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