What to Do When Watchful Wound Care Has Not Healed L. mexicana Cutaneous Leishmaniasis

Clinical Scenario

This protocol applies to cutaneous leishmaniasis caused specifically by Leishmania mexicana in patients initially managed conservatively — without antileishmanial medication — whose lesions have not fully healed.

Why Escalation Is Needed

The prior approach — simple wound care with no antileishmanial treatment, selected because disease was limited and not cosmetically disfiguring — did not achieve complete reepithelialization (healing) of the cutaneous lesion. This protocol defines the next clinical step.

Treatment Approach (Partial Overview)

For cases meeting specific lesion-count and size criteria, local treatment modalities are available. The full protocol specifies exactly which approach applies and under what conditions — see below for complete access.

Treatment Goal