Treatment of Cryofibrinogenemia with Arterial Thrombosis

Arterial thrombotic events represent a clinically significant complication in patients with cryofibrinogenemia. Their occurrence warrants a specific, ongoing maintenance approach aimed at reducing further thrombotic risk.

Clinical Scenario

This protocol is for patients with cryofibrinogenemia who have experienced arterial thrombotic complications. The nature of the thrombotic event — arterial versus venous — directly guides the choice of maintenance therapy in this condition.

Treatment Approach

Maintenance antithrombotic therapy is indicated for patients with arterial thrombotic complications in cryofibrinogenemia. The protocol specifies which agents and combination strategies apply in this setting — the complete regimen is available via the link below.

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References

DOI: 10.1093/rheumatology/kew379

The occurrence of arterial and venous thrombotic events in patients with CF justifies maintenance treatment with antithrombotic medications.

Patients with venous thrombosis apparently require administration of oral anticoagulants while patients with arterial thrombotic complications should probably be given low-dose aspirin alone or in combination with anticoagulants.

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