This protocol addresses patients with ulcerative colitis in whom an elevated colorectal lesion containing low-grade dysplasia (LGD) is identified on surveillance, and a sporadic adenoma is considered highly probable based on lesion characteristics.
In the setting of ulcerative colitis, distinguishing a sporadic adenoma from colitis-associated dysplasia is clinically significant. When the elevated lesion's morphology makes a sporadic adenoma highly probable, a defined and well-supported management pathway applies.
In this specific setting, an endoscopic intervention targeting the elevated lesion is the recommended course of action, supported by strong evidence with full agreement among guideline experts.
DOI: 10.1007/s00535-021-01776-1
If LGD is detected in an elevated lesion and sporadic adenoma is highly probable, the recommendation is to perform endoscopic resection and a detailed pathological examination (recommendation strong [agreement rate 100%], level of evidence C).
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