Colon polyp
ICD-10 K63.5  ·  ICD-11 DB35

Treatment of Colon Polyp in Familial Adenomatous Polyposis (FAP)

Clinical Scenario

Familial Adenomatous Polyposis (FAP)

This protocol addresses colon polyp management in patients with familial adenomatous polyposis. FAP encompasses both APC and MUTYH genetic variants, and each subtype carries a high rate of colorectal cancer, making timely and definitive intervention critical.

Treatment Approach

For patients with FAP, the recommended approach involves a major surgical intervention directed at definitively addressing the colorectal burden of disease. The full structured protocol specifies the procedure, timing considerations, and clinical pathway in detail.

Complete regimen and decision algorithm available via the link below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1007/s00535-021-01776-1

FAP includes both APC and MUTYH variants and there is a high rate of colorectal cancer in each subtype [112–114].

In contrast, total proctocolectomy with ileal-pouch-anal anastomosis is recommended for FAP [118].

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