Treatment of Cogan's Syndrome with Anterior Segment Ocular Involvement (Interstitial Keratitis, Anterior Uveitis) Without Systemic or Cochleo-Vestibular Disease

This protocol covers Cogan's syndrome when ocular inflammation is limited to the anterior segment — encompassing interstitial keratitis, conjunctivitis, episcleritis, scleritis, and anterior uveitis — with no cochleo-vestibular dysfunction and no systemic involvement.

Clinical scenario

Anterior segment ocular involvement (interstitial keratitis, conjunctivitis, episcleritis, scleritis, anterior uveitis) — cochleo-vestibular involvement absent, systemic involvement absent.

Treatment approach

In this setting — anterior segment disease only, without systemic or cochleo-vestibular involvement — management centres on topical steroid therapy delivered directly to the eye. The specific agents, formulations, and clinical decision points that govern this scenario are set out in full in the structured protocol.

Complete regimen, agent selection, and step-by-step guidance are available in the protocol →

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.revmed.2024.09.007

Anterior segment eye involvement (keratitis, conjunctivitis, episcleritis, scleritis, and anterior uveitis) generally benefits from topical steroid therapy only, while more posterior involvement usually requires systemic steroid therapy.

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