Treatment of Cogan's Syndrome in Patients Under 18 Years

Cogan's syndrome is a rare inflammatory condition primarily affecting the auditory system and the eyes. Its occurrence in children and adolescents is exceptionally uncommon, making structured clinical guidance for this age group particularly important.

Clinical scenario: Patient age under 18 years. With only around fifty cases reported in the literature, pediatric Cogan's syndrome is among the rarest presentations of this condition and requires age-appropriate management considerations.

Treatment approach: Management in this age group centres on steroid therapy as the initial intervention. The complete regimen — including dosing guidance, escalation criteria, and considerations for systemic involvement — is detailed in the full protocol.

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References

Cogan's syndrome is a complex condition primarily affecting the auditory system and the eyes and has been very rarely described in children, with around fifty reported cases.
Treatment relies on steroid therapy and immunosuppressants, with a preference for mycophenolate mofetil or azathioprine over cyclophosphamide in case of systemic involvement due to their tolerability profile.

DOI: 10.1016/j.revmed.2024.09.007

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