This protocol addresses Coat's disease presenting at Shields stage 5 — advanced end-stage disease — in the specific setting of a painful eye complicated by neovascular glaucoma. This represents one of the most severe clinical presentations of the condition.
Advanced end-stage Coat's disease (Shields stage 5) with a painful eye complicated by neovascular glaucoma. At this stage, structural and functional damage is extensive, and the clinical priority shifts toward managing pain and the severe complications of end-stage disease.
For this presentation, a definitive surgical procedure is the indicated approach. The full structured regimen — including the specific intervention and complete clinical decision pathway — is available via the protocol below.
DOI: 10.1159/000336906
5 Advanced end-stage disease
Advanced end-stage disease (5) with painful eye Enucleation
Enucleation may be also necessary in some cases of Coats' disease and is carried out in approximately 16% of patients with confirmed Coat's disease, complicated with neovascular glaucoma, pain, nausea and vomiting.
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