Classic Kaposi sarcoma presents with cutaneous lesions that differ in size, morphology, and location. Treatment is aimed at achieving lesion regression while maintaining quality of life, with the approach tailored to the specific characteristics of each lesion.
The primary goal is regression of KS lesions. Response is assessed by changes in tumor size, thickness, and coloration, as well as the presence or resolution of edema.
DOI: 10.1111/ddg.14788
Local KS treatment options primarily apply to individual cutaneous lesions, especially if they are symptomatic, aesthetically disturbing, or lead to functional impairment, and to patients who cannot tolerate systemic therapy because of side effects and/or comorbidities.
Numerous local treatment options are available for the treatment of individual cutaneous KS lesions, ranging from camouflage, excision, cryotherapy, radiotherapy or intralesional injections of chemotherapeutic agents, to topical therapies with various externals, which can also be used in combination.
The goal of KS treatment is usually to induce regression of the lesions, to achieve control over the course of the disease, and to reduce symptoms while maintaining quality of life and life expectancy.
In addition to subjective parameters, the size, thickness and coloration of the tumors as well as the presence of edema serve as criteria.
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