This protocol addresses patients with chronic pelvic pain syndrome who present with chronic or recurrent episodes of rectal pain or aching. The presentation meets Rome IV diagnostic criteria for primary chronic anal pain syndrome, requiring all of the following:
The preferred first-line intervention for this presentation is biofeedback therapy targeting the pelvic floor. Evidence from randomised controlled trials supports this approach over alternative interventions for patients with confirmed puborectalis tenderness. The full structured regimen — including the specific training components and clinical pathway — is available in the complete protocol.
Adequate relief of chronic rectal pain at 1 month. In patients with confirmed puborectalis muscle tenderness, substantially higher rates of adequate relief have been demonstrated with the preferred approach compared to alternative interventions.
Diagnostic criteria for primary chronic anal pain syndrome (chronic proctalgia) according to the Rome IV criteria are as follows and must include all of the following: chronic or recurrent rectal pain or aching; episodes last at least 30 minutes; and exclusion of other causes of rectal pain, such as ischaemia, inflammatory bowel disease, cryptitis, intramuscular abscess and fissure, haemorrhoids, prostatitis and coccyx pain syndrome.
Primary chronic anal pain syndrome includes the above diagnostic criteria and exhibits exquisite tenderness during posterior traction on the puborectalis muscle.
Undertake biofeedback treatment in patients with chronic anal pain. Biofeedback is the preferred treatment for chronic primary anal pain syndrome.
An RCT demonstrated that biofeedback treatment was superior to electrogalvanic stimulation and massage of the levator muscle for treating chronic primary anal pain syndrome.
In patients with tenderness of the puborectalis muscle (Rome II: 'Highly likely levator ani syndrome'), 87% reported adequate relief after one month of biofeedback versus 45% for electrogalvanic stimulation, and 22% for massage.
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