Chronic Granulomatous Disease in Dental Treatment Likely to Cause Bleeding
Patients with chronic granulomatous disease (CGD) have impaired ability to fight bacterial infections. When they require dental treatment likely to cause bleeding, specific prophylactic measures are indicated to reduce the risk of serious infection.
This protocol applies to CGD patients undergoing dental treatment likely to cause bleeding — a setting in which bleeding from the mouth poses a meaningful infectious risk in a host with defective microbial killing.
Treatment Approach
Management centres on antibiotic prophylaxis administered peri-procedurally — given before the procedure and continued for a defined window afterward. The full protocol specifies the agent, dosing, and schedule.
References
- Antibiotic prophylaxis should be prescribed for any dental treatment likely to cause bleeding: Ciprofloxacin (7.5mg/kg for a child, 500mg for an adult, oral prep.) should be given before the procedure followed by 2 doses, 12 hours apart, in the 24 hours following the procedure.
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