Colitis is one of the most common significant inflammatory complications of chronic granulomatous disease. Its presentation can closely resemble other inflammatory bowel conditions, making accurate recognition critical for appropriate management.
CGD-associated colitis may be misdiagnosed as Crohn's disease when diarrhoea, weight loss, failure to thrive, and perianal disease are the presenting features. Identifying the underlying CGD context is essential before initiating targeted treatment.
The goal is induction and maintenance of remission of colitis. Initial management involves a specific class of anti-inflammatory agents — the full regimen, drug selection, and dosing are detailed in the structured protocol.