Chronic fatigue syndrome
ICD-10 G93.3 · ICD-11 8E49

Chronic Fatigue Syndrome When Adaptive Pacing Therapy Has Not Produced Improvement

Clinical Situation

This protocol applies to patients with chronic fatigue syndrome (CFS/ME) who have been treated with adaptive pacing therapy (APT) — a structured programme that uses personalised pacing, an individually calibrated balance between activity and rest, and gradual, measured increases in daily activity — but have not achieved the expected clinical gains within the expected timeframe.

Previous Line Did Not Meet Goals
Escalation Trigger

When adaptive pacing therapy has not produced improvement in symptom severity or in the ability to perform daily activities by 3 weeks, clinical evidence supports advancing to the next structured treatment step.

Next-Line Approach
Treatment Direction & Goals

The protocol for this situation involves a structured psychological or counselling-based intervention that targets fatigue-related patterns to support recovery. The full protocol — including how the intervention is configured and what it is combined with — is available via the link below.

Instant Access to Structured Evidence-Based Regimens
References
DOI: 10.1111/bph.13702