This protocol applies to patients with higher-grade chondrosarcoma — grade II or grade III, including the clear cell variant — as well as to chondrosarcomas arising in the pelvis or axial skeleton, regardless of grade. These anatomical and histological features define a group requiring a specific, evidence-guided management approach.
The cornerstone of management for this scenario is a surgical intervention focused on achieving adequate oncological margins. The full structured protocol — including the complete sequence of steps, surgical considerations, and any additional management — is available via the link below.
Higher-grade chondrosarcomas (including clear cell chondrosarcoma) and all chondrosarcomas of the pelvis or axial skeleton should be surgically excised with wide margins.
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