A distinct subset of patients with perihilar cholangiocarcinoma — those with a tumour under 3 cm, underlying chronic liver disease (most commonly primary sclerosing cholangitis), and no evidence of extrahepatic spread — may be candidates for a specific treatment approach with intent for long-term disease-free survival.
Perihilar cholangiocarcinoma less than 3 cm in the setting of chronic liver disease — most commonly primary sclerosing cholangitis — with no extrahepatic disease confirmed.
In carefully selected patients who meet strict eligibility criteria, a surgical transplant-based strategy is the treatment of record. Full selection criteria, pre-treatment workup, and protocol details are available in the complete structured regimen.
Liver transplantation for selected patients with pCCA in the presence of chronic liver disease (most commonly primary sclerosing cholangitis), less than 3 cm in size with no evidence of extrahepatic disease results in long-term disease-free survival.
Liver transplantation is a potential treatment option for selected patients with pCCA or iCCA.
DOI: 10.1136/gutjnl-2023-330029
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