Treatment of Chickenpox in Pregnancy
Chickenpox (varicella) acquired during pregnancy presents a distinct clinical challenge.
The combination of active varicella infection and the physiological changes of pregnancy
significantly elevates the risk of serious complications compared with the general adult population.
Clinical Situation
Pregnant women with chickenpox are at significant risk of varicella pneumonitis and severe disease.
This population requires prompt assessment and a carefully considered management approach.
Treatment Approach
Oral antiviral therapy is the current recommendation for mild disease in pregnancy, combined with
symptomatic relief measures. For cases warranting a different approach, second-generation antiviral
agents may be considered on expert advice.
Full dosing schedule, regimen sequence, and specialist guidance are in the complete protocol →
References
DOI: 10.1016/j.jinf.2008.03.004
- Pregnant women are at significant risk of varicella pneumonitis and severe disease.
- For mild disease in pregnancy oral aciclovir is the current recommendation in the UK.
- However, second generation antiviral drugs should be considered on expert advice.
- Supportive therapy, such as anti-pruritic drugs can be helpful for all age groups.
- Mouthwashes and soothing topical lotions, plus anaesthetic gels for the genital area if there is mucosal involvement, are also useful for symptomatic treatment.
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