Cerebral meningioma
ICD-10 D32.0 ICD-11 2A01.0Z

WHO Grade 2 (Atypical) Meningioma When Surgery Did Not Fully Relieve Symptoms

WHO grade 2 (atypical) meningioma carries a higher risk of recurrence and requires a more active management strategy. When initial surgical resection does not achieve the intended goals, further treatment is mandatory.

Clinical scenario

WHO grade 2 (atypical) meningioma. In meningioma WHO grade 2, therapy is mandatory.

Previous treatment & why it was insufficient

Surgery was performed as the first option — both to obtain tissue for diagnosis and to remove mass effect, targeting a Simpson grade I resection. The goals of relieving neurological symptoms and mass effect were not fully met, prompting escalation to the next treatment step.

Next step — partial overview

A form of radiotherapy delivered in fractions is part of the approach for this scenario.

Specific indications, sequence, and full protocol details are available in the complete regimen.

References

In meningioma WHO grade 2, therapy is mandatory.

For WHO grade 2 meningioma with a Simpson IV-V resection, RT is recommended.

Patients with recurrent or atypical meningiomas should receive fractionated radiotherapy.

DOI: 10.1093/neuonc/noab150

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