Cerebral meningioma that is symptomatic or enlarging requires a structured first-line treatment strategy aimed at relieving neurological burden and addressing the tumor directly.
Surgery is the first therapeutic option when treatment is indicated — the specific surgical strategy, including criteria for combined approaches, is detailed in the full protocol.
Relief of neurological symptoms and mass effect. Neurological and cognitive symptoms and signs may be reversed.
DOI: 10.1093/neuonc/noab150
The primary treatment for the majority of symptomatic or enlarging meningiomas is surgery.
Surgery should be considered as the first therapeutic option in tumors of all WHO grades if therapy is indicated.
Successful surgery achieves 2 goals — relief of neurological symptoms and mass effect and provision of tissue for diagnosis.
Neurological and cognitive symptoms and signs may be reversed.