CNS Metastases with Poor Performance Status and Expected Survival Under 3 Months

This protocol addresses patients with central nervous system metastases who have poor performance status, an expected prognosis of less than 3 months, and multiple brain metastases that are not eligible for stereotactic radiosurgery (SRS).

Clinical Scenario

Multiple brain metastases — not eligible for stereotactic radiosurgery
Poor performance status
Expected survival less than 3 months

Management Approach

In this setting, a supportive and palliative care framework is the recommended basis of management. The full protocol specifies the complete evidence-based approach for this scenario.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.annonc.2021.07.016

Supportive care with omission of WBRT should be considered in patients with multiple BMs not eligible for SRS and poor PS.

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